Cholinesterase inhibitors in dementia: yes, no, or maybe?

Cholinesterase inhibitors in dementia: yes, no, or maybe?

Often it is not for the benefit of patients, when a clinical issue is debated in public domain. Currently, patients with dementia who are considered for treatment with one of the cholinesterase inhibitors are in danger of being crushed between clinical opinion leaders, national guidelines, pharmaceutical companies and politicians. After a review of the cost effectiveness of cholinesterase inhib...

Editorial: Madness and creativity—yes, no or maybe?

There is something inherently appealing about the idea that creativity and psychopathology are inextricably linked. The eagerness with which this idea is perpetuated and often exaggerated was evidenced most recently in the media frenzy following the publication of a genome-wide association study which demonstrated what in effect was a modest genetic association between creativity and psychosis ...

Antidepressants in bipolar depression: yes, no, maybe?

Antidepressants are widely used in the treatment of bipolar depression despite relatively meagre evidence for their efficacy and significant concerns that their prescription can precipitate an acute affective switch into mania/hypomania and that long-term administration can lead to mood instability. Therefore, the use of antidepressants to treat bipolar depression is an important but contentiou...

New Medicine Based on New Biology: Maybe Yes, Maybe No

For them, traditional biologists and medical scientists committed a gross scientific error by overlooking quantum physics as being too weird, mind bending and unpredictable for biological systems. The basis of quantum physics is that, at the sub-atomic level, matter does not exist with certainty. It only exists as a tendency to exist in particle or wave form as maybe yes or maybe no. This appli...

Genetically Modified Food: Yes or No?